Fibrosarcoma in Mice

When luteolin is supplemented in the diet of these mice, fibrosarcoma rates decline by 40%. The scientists stated that mode of action may be through their influence on the initiation and promotion phases of the carcinogenic process coupled with enhancement of the detoxification process. When a group of plant extracts were evaluated to ascertain if they could maintain normal cell regulation, luteolin demonstrated the highest anti-proliferative activity.