There have been studies on luteolin for decades.
We collected all sorts of references from all over the world to help prove the benefits of luteolin and similar flavonoids. Add it to your diet naturally or try natural luteolin supplements for neurological and immune support.
1) Hoppe, H.A. (1975) Drogenkunde Band 1 Angiospermien, 8th ed., DeGryter, Berlin, New York.
2) Teuscher E. (1989) Pharmakognosie - Biogene Arzneimittel, 3rd ed., Akademie Verlag Berlin.
3) Achterrath-Tuckermann, U.; Kunde, R.; Flaskamp, E.; Isaac, O.; Thiemer, K. (1980) Planta Med. 39, 38-50.
4) Kraft, K. (1997) Phytomedicine 4(4), 369-378.
5) Bashir, A.K.; Abdalla, A.A.; Wasfi, I.A.; Hassan, E.S.; Amiri, M.H.; Crabb, T.A. (1994) Int. J. Pharmacog. 32(4), 366-372.
6) Shin, K.H.; Kang, S.S.; Kim, H.J.; Shin, S.W. (1994) Phytomedicine 1(2), 145-147.
7) Glinkowska, G.; Strzelecka H. (1987) Acta Pol. Pharm. XLIV(5), 476.
8) Czeczot, H.; Tudek, B.; Kuszelak, T.; Szymczyk, T.; Dobrowolska, B.; Glinkowska, G. (1990) Mutation Res. 240, 209-216.
9) Nagao, M.; Morita, N.; Yahagi, T.; Shimizu, M.; Kuroyanagi, M.; Fukuoka, M. (1981) Environ. Mutagen. 3(4), 401-419.
10) Sanchez de Rojas, V.R.; Somoza, B.; Ortega, T.; Villar, A.M. (1996) Planta Med. 62(3), 272-274.
11) Son, K.H.; Park, J.O.; Chung, K.C.; Chang, H.W.; Kim J.S. (1992) Arch. Pharm. Res. 15, 365-370.
12) Yanoshita, R.; Chang, H.W.; Son, K.H.; Kudo, I.; Samejima Y. (1996) Inflamm. Res. 45, 546-549.
12) Yanoshita, R.; Chang, H.W.; Son, K.H.; Kudo, I.; Samejima Y. (1996) Inflamm. Res. 45, 546-549.
13) Perez-Garcia, F., Adzet, T., Canigueral, S., Free Radic. Res., (2000), 33(5), 661-665.
14) Rice-Evans, C.A.; Miller, N.J.; Paganga, G. (1997) Trends in Plant Science 2, 152-159.
15) Miller, N.J. (1996) "Natural Antioxidants and Food Quality in Atherosclerosis and Cancer Prevention", Kumpulainen, J.T.; Salonen, J.T. eds; The Royal Society of Chemistry, 256-259.
16) Igile, G.O.; Oleszek, W.; Jurzysta, M.; Burda, S.; Fafunso, M.; Fasanmade, A.A. (1994) J. Agric. Food Chem. 42(11), 2445-2448.
17) Cotelle, N.; Bernier, J.L.; Catteau, J.P.; Pommery, J.; Wallet, J.C.; Gaydou, E.M. (1996) Free Radic. Biol. Med. 20(1), 35-43.
18) Tournaire, C.; Croux, S.; Maurette, M.-T.; Beck, I.; Hocquaux, M.; Braun, A.M.; Oliveros, E. (1993) J. Photochem. Photobiol. B: Biol. 19, 205-215.
19) Cos, P.; Calomme, M.; Hu, J.P.; Cimanga, K.V.; .Poel, B.; Pieters, L.; Vlietinck, A.J. (1998) J. Nat. Prod. 61, 71-76.
20) Cai, Q.; Rahn, R.O.; Zhang, R. (1997) Cancer Lett. 119, 99-107.
21) Kong, L. D., Wolfender, J. L., Cheng, C. H., Hostettmann, K., Tan, R. X., Planta Med., (1999), 65(8), 744-746.
22) Yokozawa, T.; Dong, E.; Liu, Z.W.; Shimizu, M. (1997) Phytother. Res. 11, 446-449.
23) Galvez, J.; Dela Cruz, J.P.; Zarzuelo, A.; De la Cuesta, F.S. (1995) Pharmacology 51(2), 127-133.
24) Cholbi, M.R.; Paya, M.; Alcaraz, M.J. (1991) Experientia 47(2), 195-199.
25) Gebhardt, R. (1995) 43rd Annual Congress, Soc. Med. Plant. Res., Halle, Germany.
26) Schussler, M., Holzl, J., Fricke, U. (1995). Arzneimittelforschung, 45( 8), 842-845.
27) Occhiuto, F.; Busa, G.; Ragusa, S.; De Pasquale, A. (1991) Phytother. Res. 5, 9-14.
28) Du, S. H., Jin, J. S., Chin. Herb. Med. J., (1996), 27, 416-417.
29) Wang, L. Y., Han, C. H., Wang, P., Li, G. Y., Xu, S. Y. (1986) Chin. Pharmacol. Bull, 2, 34-36.
30) Lin, C.N.; Kuo, S.H.; Chung M.I. (1997) J. Nat. Prod. 60, 851-853.
31) Duarte, J. Perez, Vizcaino F., Utrilla, P., Jimenez, J., Tamargo, J., Zarzuelo, A., Gen Pharmacol., (1993), 24(4), 857-862.
32) Chan, E. C., Pannangpetch, P., Woodman, O. L., Cardiovasc. Pharmacol., (2000), 35(2), 326-333.
33) Chang, W.C., Hsu, F. L., Prostaglandins Leukot Essent Fatty Acids, (1992), 45(4), 307-312.
34) Kaneko, T., Baba, N., Biosci Biotechnol. Biochem., (1999), 63(2), 323-328.
35) Post, J.F.M.; Varma, R.S. (1992) Cancer Lett. 67(2-3), 207-213.
36) Ramanthan, R.; Das, N.P.; Tan, C.H. (1993) Int. J. Oncol. 3, 115-119.
37) Elangovan, V.; Ramamoorthy, N.; Balasubramanian, S.; Sekar, N.; Govindasamy, S. (1994) Indian J Pharmacol. 26(4), 266-269.
38) Ryu, S.Y.; Choi, S.U.; Lee, C.O.; Lee, S.H.; Ahn, J.W.; Zee, O.P. (1994) Arch.Pharm. Res. 17(1), 42-44.
40) Ubeda, A.; Esteve, M.L.; Alcaraz, M.J.; Cheeseman, K.H.; Slater, T.F. (1995) Phytother. Res. 9(6), 416-420.
41) Elangovan, V.; Ramamoorthy, N.; Balasubramanian, S.; Sekar, N.; Govindasamy, S. (1994) Indian J Pharmacol. 26(4), 266-269.
42) Edenharder, R.; Rauscher, R.; Platt, K.L. (1997) Mutation Res. 379, 21-32.
43) Taj, S.; Nagarajan, B. (1996) Mutation Res. 369(1,2), 97-106.
44) Elangovan, V.; Sekar, N.; Govindasamy, S. (1995) Cancer Lett. 87, 107-113.
45) Colerangle, J.B.; Roy, D. (1995) Int. J. Oncol. 7, 1361-1366.
46) Chen, C.W.; Palangat, M.; Oberley, T.D.; Roy, D. (1996) Int. J. Oncol. 9(4), 811-814.
47) Liu, Y. C., Hung, C. F., Yeh, F. T., Food Chem Toxicol., (2001), 39(7), 641-647.
48) Samejima, K., Kanazawa, K., Ashida, H., Danno, G., J. Agric. Fodd Chem., (1995), 43(2), 410-414.
49) Tachibans, K.; Okada, Y.; Okuyama, T. (1995) Nat. Med. 49(3), 266-268.
50) Yamamoto H., Food style, 1998, 21(2), 71-74. Yamamoto H, Sakakibara J, Nagatsu A, Sekiya, J. Agric. Food Chem., 1998, 46, 3, 862-865.
51) Chen M, Jin W, Dai L, Xu S ,Zhongguo Yaolixue Yu Dulixue Zazhi, 1986, 1(1), 46-52.
52) Yamamoto H., Food style, 1998, 21(2), 71-74. Yamamoto H, Sakakibara J, Nagatsu A, Sekiya, J. Agric. Food Chem., 1998, 46, 3, 862-865.
53) Tordera M, Ferrandiz ML, Alcaraz, Z Naturforsch [C]., 1994, 30; 49(3-4):235-40.
54) Merfort, I.; Heilmann, J.; Hagedorn-Leweke, U.; Lippold, B. C. (1994). Pharmazie 49(7), 509-11.
55) Jin, W. Z., Dai, L. M., Li, Y. F., Chen, M. Z., Acta Anhui Med Univ, (1985), 20, 14-15.
56) Kim, H. K., Cheon, B. S., Kim, S. Y., Kim, H. P., Biochem. Pharmacol., (1999), 58, 759-765.
57) Kim, J. S.; Kwon, C. S., and Son, K. H., Biosci Biotechnol Biochem., 2000, 64(11):2458-61.
58) Cheong H, Ryu S-Y, Oak M-H, Cheon S-H, Yoo G-S, Kim K-M, Arch Pharmacol Res, 1998, 21, 4, 478-480.
59) Rainova L, Gakhniyan R, Farmatsiya (Sofia), 1978, 28(5), 39-42.
60) Varma, S.D.; Mikumi, I.; Kinoshita, J.H. (1975) Science 186, 1215-1221.
61) Matsuda, H.; Cai, H.; Kubo, M.; Tosa, H.; Linuma, M. (1995) Bio. Pharm. Bull. 18(3), 463-466.
62) Kimata M, Shichijo M, Miura T, Serizawa I, Inagaki N, Nagai H, Clin Exp Allergy, 2000, 30(4):501-8
63) Kimata M, Inagaki N, Nagai H, Planta Med., 2000, 66, 1, 25-29.
64) Yamada K, Matsuo N, Shoji K et al., ACS Symp Ser, 1998, 701, 198-208.
65) Amellal M, Bronner C, Briancon F et al., Planta Med, 1985, 1, 16-20.
66) Shen C-H., Yao Hsueh T’ung Pao, 1980, 15, 12, 36.
67) Hiremath, S. P., Badami, S., Hunasagatta,S. K., Patil, S. B.(2000) Eur. J. Pharmacol 391(1-2), 193-197.
68) Wleklik, M.; Luczak, M.; Panasiak, W.; Kobus, M.; Lammer-Zarawska, E. (1988) Acta Virol. 32(6), 522-525.
69) Vrijsen, R.; Everaet, L.; Boeye, A. (1988) J. Gen. Virol. 69(7), 1749-1751.
70) Kusumoto, I.T.; Hattori, M.; Miyaichi, Y.; Tomimori, T.; Hanaoka, M.; Namba, T. (1991) Shoyakugaku Zasshi 45(3), 240-254.
71) Tsou, M. F., Chen, G. W., Hung, C. F., Microbios, (2001), 104, 408, 87-97.
72) Simoes, C. M., Schenkel, E. P., Bauer, L., Langeloh, A., J. Ethnopharmacology, (1988), 22(3),, 281-293.
73) Chung, J. G., hsia, T. C., kuo, H. M., Toxicol in vitro, (2001), 15(3), 191-198.
74) Ciaceri, G., Attaguile, G., Minerva Med., (1972), 63(29), 1665-1668.
75) Saller, R.; Reichling, J.; Hellenbrecht, D. (1995) Phytotherapie - klinische, pharmakologische und pharmazeutische Grundlagen, K.F. Haug Verlag, Heidelberg.
76) Shimoi, K.; Masuda, S.; Furugori, M.; Esaki, S.; Kinae, N. (1994) Carcinogenesis 15(11), 2669-2672.
77) Horiuchi, T., Fujiki, H., Hakii, H., Suganuma, M., Yamashita, K. Sugimura, T., Jpn J. Cancer Res., (1986), 77(6), 526-531.
78) Kuppusamy, U.R; Das, N.P. (1991) Experientia 47(11-12), 1196-1200.
79) Zhou, Z. D., Wang, L. Y., Wang, P. (1979) Chin. Herb Med. Commun. 10, 35.
80) Annui Cooperation Group, Preliminary experimental study of Aruga decumbens Thunb. against chronic bronchitis, (1973) Chin. Herb. Med. Commun. 2, 18-23.
81) Amellal, M.; Bronner, C.; Briancon, F.; Haag, M.; Anton, R.; Landry, Y. (1994) Planta Med. 1, 16-20.
82) Kawasaki, M.; Toyda, M.; Teshima, R.; Sawada, J.; Hayashi, T.; Arisawa, M.;Shimzu, M. (1994) Shokuhin Eiseigaku Zasshi (J. Food Hyg. Soc. Japan) 35(5), 497-503.
83) Mittra, B., Saha, A., Chowdhury, A. R., Pal, C., Mandal, S., Mukhopadhyay, S., Bandyopadhyay, S., Majumder, H. K., Mol. Med., 6(6), 527-541.
84) Block, L. C.; Santos, A. R.; de Souza, M. M.; Scheidt, C.; Yunes, R. A.; Santos, M. A.; Monache, F. D.; Filho, V. (1998). J Ethnopharmacol. 61(1), 85-9.
85) Pieroni, A.; Pachaly, P.; Huang, Y.; Van Poel, B., and Vlietinck, A. J., J Ethnopharmacol., 2000, 70(3):213-7.
86) Rump, A. F.; Schussler, M.; Acar, D.; Cordes, A.; Theisohn, M.; Rosen, R.; Klaus, W., and Fricke, U, Gen Pharmacol., 25(6):1137-42.
87) Park, K. Y.; Lee, S. H.; Min, B. K.; Lee, K. S.; Choi, J. S.; Chung, S. R.; Min, K. R., and Kim, Y, Planta Med., 1999, 65(5):457-9.
88) Zarzuelo A, Jimenez I, Gamez MJ, Utrilla P, et al., Life Sciences, 1996, 58, 25, 2311-2316.
89) Shimoi, K.; Saka, N.; Kaji, K.; Nozawa, R., and Kinae, N., Biofactors, 2000, 12(1-4):181-6.
90) Chen, M. Z., Feng, R. J., Gu, Y. Z., Guang, L. X., Zhen, Y. W., Wang, G. B., Li, W. P., Xu, S. Y. (1986) Chin. Pharmacol. Bull. 2, 15-20.
91) Wang (2000) Drugs of the future. 25(2), 146-149.
92) Spencer, J. P. E., Chowrimootoo, G., Choudhury, R, Debnam, E. S., Kaila Srai, S., Rice-Evans, C., FEBS Lett., (1999), 458, 224-230.
93) Peng, H.; Xiang, S.; Bi, Z. (1981) Yao Hsueh T´ung Pao 16(ISS 2), 11-13.
94) Chavant, L.; Combier, H.; Cros, J. (1975) Plant. Med. Phytother. 9(4), 267-272.
95) Dai, L. M., Cheng, H., Li, W. P., Liu, S. Q., Chen, M. Z., Xu, S. Y. (1985) Acta Anhui Med. Univ. 20, 1-3.
96) Fiszer-Szafaraz, B. (1984) Analyt. Biochem. 143, 76-84.
98) MacGregor, J.T.; Jurd, L. (1978) Mutation Res. 54, 297-309
99) Gebhardt R. New experimental results in the action of artichoke leaf extract. Zeitschrift fur Allgemeinmed 1996;72:20–3
100) Brown JE, Rice-Evans CA. Luteolin rich artichoke extract protects low density lipoprotein from oxidation in vitro. Free Radical Research 1998 Sep;29(3):247-55. [source]
101) Yanoshita R, et al. Inhibition of lysoPAF acetyltransferase activity by flavonoids. Inflamm Res 1996 Nov;45(11):546-9 [source]
102) Ma JY, et al. A sesquiterpene lactone glucoside from Ixeris denticulata f. pinnatipartita. Phytochemistry 1999 Jan;50(1):113-5 [source]
103) Matsukawa Y, et al. Genistein arrests cell cycle progression at G2-M. Cancer Res 1993 Mar 15;53(6):1328-31 [source]
104) Post JF, et al. Growth inhibitory effects of bioflavonoids and related compounds on human leukemic CEM-C1 and CEM-C7 cells. Cancer Lett 1992 Dec 24;67(2-3):207-13. [source]
105) Makino T, et al. Inhibitory effect of Perilla frutescens and its phenolic constituents on cultured murine mesangial cell proliferation. Planta Med 1998 Aug;64(6):541-5. [source]
106) Shimoi K, et al. Radioprotective effects of antioxidative plant flavonoids in mice. Mutat Res 1996 Feb 19;350(1):153-61. [source]
107) Garcia-Closas R, et al. Intake of specific carotenoids and flavonoids and the risk of gastric cancer in Spain. Cancer Causes Control 1999 Feb;10(1):71-5. [source]
108) Walaszek Z, et al. D-Glucaric acid content of various fruits and vegetables and cholesterol-lowering effects of dietary D-glucarate in the rat. Nutrition Research (United States) 1996, 16/4 (673-681).
109) Oredipe OA, et al. Dietary glucarate-mediated inhibition of initiation of diethylnitrosamine-induced hepatocarcinogenesis. Toxicology; 74 (2-3). 1992. 209-222.
110) Walaszek Z, et al. Dietary glucarate-mediated reduction of sensitivity of murine strains to chemical carcinogenesis. Cancer Lett 1986 Oct;33(1):25-32. [source]
111) Hirano T, et al. Antiproliferative effects of synthetic and naturally occurring flavonoids on tumor cells of the human breast carcinoma cell line, ZR-75-1. Res Commun Chem Pathol Pharmacol 1989 Apr;64(1):69-78. [source]
112) Kuiper GG, et al. Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta. Endocrinology 1998 Oct;139(10):4252-63. [source]
113) Noroozi M, et al. Effects of flavonoids and vitamin C on oxidative DNA damage to human lymphocytes. Am J Clin Nutr 1998 Jun;67(6):1210-8. [source]
114) Wang IK, et al. Induction of apoptosis by apigenin and related flavonoids through cytochrome c release and activation of caspase-9 and caspase-3 in leukaemia HL-60 cells. Eur J Cancer 1999 Oct;35(10):1517-25. [source]
115) Takahashi T, et al. Structure-activity relationships of flavonoids and the induction of granulocytic- or monocytic-differentiation in HL60 human myeloid leukemia cells. Biosci Biotechnol Biochem 1998 Nov;62(11):2199-204. [source]
116) Boege F, et al. Selected novel flavones inhibit the DNA binding or the DNA religation step of eukaryotic topoisomerase I. J Biol Chem 1996 Jan 26;271(4):2262-70. [source]
117) Kawaii S, et al.Effect of citrus flavonoids on HL-60 cell differentiation. Anticancer Res 1999 Mar-Apr; 19(2A):1261-9. [source]
118) Yin F, et al. Signal pathways involved in apigenin inhibition of growth and induction of apoptosis of human anaplastic thyroid cancer cells (ARO). Anticancer Res 1999 Sep-Oct;19(5B):4297-303. [source]
119) Yin F, et al. Growth inhibitory effects of flavonoids in human thyroid cancer cell lines. Thyroid 1999 Apr;9(4):369-76. [source]
