Healthy Methylation
Enzymatic and genetic activity throughout the body depends on the continuous re-methylation of DNA. The age related breakdown of youthful methylation metabolism predisposes the body to a wide range of degenerative diseases. Maintaining healthy methylation patterns protects against DNA mutations that damage cells and can cause cancer.
Read MoreFibrosarcoma in Mice
When luteolin is supplemented in the diet of these mice, fibrosarcoma rates decline by 40%. The scientists stated that mode of action may be through their influence on the initiation and promotion phases of the carcinogenic process coupled with enhancement of the detoxification process. When a group of plant extracts were evaluated to ascertain if…
Read MoreFlavonoids and Vitamin C
A study assessed the antioxidant potencies of several dietary flavonoids compared with vitamin C. Pretreatment with all flavonoids and vitamin C produced dose-dependent reductions in oxidative DNA damage. When ranked in order of potency, luteolin was two times more effective than vitamin C by the Trolox test and more effective than seven other flavonoids in…
Read MoreInflammation, TNF-alpha, and Apoptosis
When compared to other flavonoids, only luteolin and quercetin inhibited platelet-activating factor and suppressed a type of inflammatory response induced by allergens by inhibiting lipoxygenase. Luteolin inhibited the excess production of TNF-alpha, which directly causes inflammation and apoptosis (cell death). The scientists who conducted the study concluded that luteolin could be used to develop a…
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